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Atorvastatin calcium intermediates
Atorvastatin derivative
Fluvastatin sodium intermediates
Rosuvastatin calcium intermediates
Pitavastatin calcium intermediates
Ezetimibe intermediates
Organic silicon
Product output list

 
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Intermediates ApIs Organic silicon

Intermediates

NO.

Chemical Name

CAS NO.

Atorvastatin Intermediates

Ats-4

Ehyl-4-(-)chloro-3-hydroxybutyrate

86728-85-0

Ats-5

(R)-4-cyano-3-hydroxybutyric acid ethyl ester

141942-85-0

Ats-8

(4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

125971-94-0

Ats-9

(4R,Cis)-1,1-dimethylethyl6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-Acetate

125995-13-3

M-1

methyl isobutyl acetate

42558-54-3

M-2

4-methyl-3-oxo-N-phenyl pentanamide

124401-38-3

M-3

4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide

125971-57-5

M-4

4-fluoro-a-[2-methyl-1-oxopropyl]-γ-oxo-N,β- diphenylbenzene butaneamide

125971-96-2

M-K

3-Ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide

54016-70-5

L-1

(4R-cis)-1,1-dimethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-isopropyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate

125971-95-1

L-2

(4R-cis)-1,1-dimethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-isopropyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dihydroxy-4-acetate

134395-00-9 
L-3    

L-4

(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3 ,5 -Dihydroheptanoic Acid, calcium salt (2:1) Trihydrate

134523-03-8

L-5

(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5-Dihydroheptanoic Acid, calcium salt

134523-03-8

L-6

5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide

125995-03-1

L-7

(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5-Dihydro heptanoic Acid

134523-00-5

L-8 (3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3 ,5 -Dihydroheptanoic Acid, Sodium salt  
FLUVASTATIN INTERMEDIATES

F-1

3-(4-Fluorophenyl)-1-isopropyl-1H-Indole

93957-49-4

F-2

(E)-3-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indole-2-yl] Propenal

93957-50-7

F-3

T-BUTYL(E)-7-[3'(4''-FLUOROPHENYL)-1'-METHYLETHYL-INDOL-2'-YL] -3-HYDROXY-5-OXO-6-HEPTENOATE

93957-52-9

F-4

Tert-butyl(E)-3,5-Dihydroxy-7-[3-(4-Fluorophenyl)-1- Methylethyl-Indol-2'-yl] Hept-6-enoate

93957-53-0

F-5

(E)-3,5-dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethyl-indol-2'-yl] hept-6-enoate

93957-55-2

ROSUVASTATIN INTERMEDIATES
C-2

(4R-Cis)-6-[(chlorite)methyl]-1,3- dihydrosy -4-Acetic Acid,1,1-Diemthyethyl Ester

 
C-3

(4R-Cis)-6-[( chlorite)methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Diemthyethyl Ester

 

C-4

(4R-Cis)-6-[(Acetyloxy)methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Diemthyethyl Ester

154026-95-6

C-5

(4R-Cis)-6-Hydroxymethyl-2,2-Dimethyl-1,3-Dioxane-4-AceticAcid,
1,1-Dimethyethyl Ester

124665-09-0

C-6

(4R-cis)-6-formadehydel-2,2-dimethyl-1,3-dioxane-4-acetic acid,1,1-dimethylethyl ester

124752-23-4

J-3

(3R)-3-[(terbutyldimethylsilyl)oxy]glutaric anhydride

91424-40-7

J-4

(3R)-3-[(tert-butyldimethylsily)oxy]pentanedioate-1-Methylmonoester

109744-49-2

J-5

1,5-Ethoxycarbonylmethyl-(3r)-3-tert-butyl-dimethylsilyloxy pentanedioate

158275-79-7

J-6

Methyl(3r)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidene hexanoate

147118-35-2

H-1

7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester

147118-38-5

H-2

Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate

147118-39-6

H-3

(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid,Methyl ester

147118-40-9

Na salt

(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl]-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-3,5-dihydroxy-6-heptane acid,Sodium

147098-18-8

Z-5 Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(n-methylamino) pyrimidine-5-carboxylate  

Z-6

Methyl-4-(4-Fluorophenyl)6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl)amino] pyrimidine-5-Carboxylane

289042-11-1

Z-7

4-(4-Fluorophenyl)-6-isopropyl-2-[ (N-Methyl-N-Methylsulfonyl)amino]pyrimidine-5-yl-methonol

147118-36-3

Z-8

Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine

799842-07-2

Z-8.1

4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino] pyriminl-5-yl- phosphine oxide

289042-10-0

Z-8.2

Triphenyl[4-(4-fluorophenyl)-6-isopropyl-2-[(2-n-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methyl]phosphine bromine

885477-83-8

Z-9

4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylSulfonyl amino)pyrimidine-5-carboxaldehyde

147118-37-4

R-1

7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,dimethylethyl ester

289042-12-2

R-2

(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid, dimethylethyl ester

355806-00-7

R-3

(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl] -3,5-dihydroxy-6-Heptenoic amine

 

R-4

7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5    -dihydroxy-hept-6-enoic acid sodium salt

147098-18-8
Acid 7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid 287714-41-4

R

(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Heptenoic calcium

147098-20-2

PITAVASTATIN INTERMEDIATES
PA 2-Amino-4'-fluorobenzophenone 3800-06-4
PB Methyl 2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate 121659-86-7

P-0

Ethyl-2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate

148516-11-4

P-1

2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

121660-11-5

P-2

2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxaldehyde

121660-37-5

PB2

2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-MethylBr

154057-56-4

PB3

2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-2-phenyloxophorusmethyl

146578-99-6

PB4

(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-2,2-Dimethyl-1,3-dioxane-6-heptenoic acid,1,1-dimethylethyl ester

147489-06-3

PB5

(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydrosy-6-heptenoic acid,1,1-dimethylethyl ester

586966-54-3

PB6

(4R,6S,E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl-ethenylvinyl]-4-hydroxyl-3,4,5,6-H-2H-pyran-2-etone 141750-63-2

PB7

(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydrosy-6-heptane acid,(+)phenyl ethylamine 147511-70-4
PC2 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propopenenitrile 256431-72-8
PC3 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal 148901-68-2
PC4 Ethyl (E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate 148901-69-3
PC5 Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-hept-6-enoate 172336-32-2
  Pitavastatin calcium: (+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3 -quinolyl]-3,5-dihydroxy-6-heptenoate} 147526-32-7
K3 (4R-Cis)-6-Chlorin-2,2-Dimethyl-1,3-Dihydrosy-4-acetic acid,1,1-dimethyl ethyl ester  
K4 (4R-Cis)-6- Chlorin-2,2-Dimethyl-1,3-Dioxane-4-acetic acid,1,1-dimethyl ethyl ester  
K5

(4R-cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-aceticacid,1,1-dimethylethyl ester

124665-09-0
K6 (4R-cis)-6-formaldehydel-2,2-dimethyl-1, 3-dioxane-4-acetic acid,1,1-dimethylethyl ester 124752-23-4
EZETIMIBE

E-1

(4S)-3-[5-(4-fluorophenyl)1,5-dioxophentyl]-4-phenyl-2-oxazolidinone

189028-93-1

E-2

4{[(4-fluorophenyl)imino]methyl}phenol

3382-63-6

E-3

3-[(2R,5S)-5-(4-fluorophenyl)-2-{(S)-[4-fluorophenyl]Amino}
[4-(trimethylsily)-oxy]pentyl]methyl-1-2oxo-5-(trimethylsilyl)
-oxo]penyl]-4-phenyl-(4S)-2-oxazolidinone

272778-12-8

E-4

N-[(4-fluorophenyl)-imino]-4-benzyloxyphenyl

 

E-5

Synthesis Of transmethyl-3-{3-[2-oxo-4(benzyloxyphenyl)
-1-(4-fluorophenyl)-azetidinone]}propionate

 

E-6

synthesis of trans-1-(4-fluorophenyl)-3-[3-oxo-3(4-fluorophenyl)
propyl-(4-benzyloxyphenyl)]-2-azetidinome

190595-65-4

E-7

synthesis of trans-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-
hydroxypropyl-(4-benzyloxyphenyl)]-2-azetidinome

163222-32-0

E 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one 163222-33-1
 

Triethyl borane

97-94-9

 

N-Butyllithium

109-72-8

 

Tert-Butyldimethylsilyl chloride

18162-48-6

 

T-Butyl diphenyl chlorosilane

58479-61-1

 

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